Exosome Treatment Portsmouth
Exosome therapy is one of the most advanced skin treatments available in Portsmouth right now. Our qualified, experienced & insured practitioners apply or inject an exosome solution into the skin, triggering cellular repair, stimulating collagen production and encouraging the skin to regenerate from within.
Split the cost into 3 monthly payments with 
. 0% interest.
Exosomes are extracellular vesicles derived from stem cells. They act as biological messengers, carrying instructions between cells that tell the skin to repair, rebuild and produce collagen. Where older treatments like PRP rely on growth factors drawn from your own blood, exosome therapy works at the level of cellular signalling. The result is a more targeted stimulus for regeneration, with less dependence on the body's starting condition.
At Changes Clinic, exosome treatment sits within our skin tightening and rejuvenation offer. We use it alongside and after treatments like HIFU, RF microneedling, polynucleotides and skin boosters to amplify and extend results. It can also be used as a standalone treatment for clients who want a next-generation approach to skin health.
At Changes Clinic, exosome treatment sits within our skin tightening and rejuvenation offer. We use it alongside and after treatments like HIFU, RF microneedling, polynucleotides and skin boosters to amplify and extend results. It can also be used as a standalone treatment for clients who want a next-generation approach to skin health.
What exosome treatment does
When we introduce exosomes into the skin, they activate several processes at once.
Cellular signalling: Exosomes carry messenger RNA and proteins that direct skin cells to switch on repair pathways. This is the same kind of cellular activity that declines naturally as we age, and exosome therapy is designed to reactivate it.
Collagen stimulation: One of the primary outcomes is an increase in collagen and elastin production. Over the weeks following treatment, the skin becomes firmer, more elastic and visibly smoother.
Skin repair and regeneration: Exosomes speed up the skin's natural repair cycle. For clients recovering from RF microneedling, laser or chemical peels, this can shorten downtime and improve the final result. Applied to healthy skin without a prior procedure, exosomes work gradually and cumulatively, improving texture, tone and radiance over time.
What you can expect to see: Improved skin texture and tone, a reduction in fine lines and early wrinkles, increased firmness, and a more even, luminous complexion. For scalp treatments, exosomes support the conditions for healthier hair growth and reduced shedding.
Cellular signalling: Exosomes carry messenger RNA and proteins that direct skin cells to switch on repair pathways. This is the same kind of cellular activity that declines naturally as we age, and exosome therapy is designed to reactivate it.
Collagen stimulation: One of the primary outcomes is an increase in collagen and elastin production. Over the weeks following treatment, the skin becomes firmer, more elastic and visibly smoother.
Skin repair and regeneration: Exosomes speed up the skin's natural repair cycle. For clients recovering from RF microneedling, laser or chemical peels, this can shorten downtime and improve the final result. Applied to healthy skin without a prior procedure, exosomes work gradually and cumulatively, improving texture, tone and radiance over time.
What you can expect to see: Improved skin texture and tone, a reduction in fine lines and early wrinkles, increased firmness, and a more even, luminous complexion. For scalp treatments, exosomes support the conditions for healthier hair growth and reduced shedding.
What to expect
The treatment process
Your treatment starts with a free consultation. We assess your skin, talk through your concerns, and confirm whether exosome therapy is the right fit — or whether it would work best as part of a combined plan.
The exosome solution is applied directly to the skin or injected, depending on the area and the outcome we are working towards. For scalp treatments, the solution is delivered into the dermal layer. For facial rejuvenation, we often apply exosomes immediately after a microneedling procedure to maximise absorption and results.
The appointment typically takes 30 to 60 minutes, including preparation and aftercare guidance.
Sessions needed
Most clients start with a course of two to three sessions, spaced four to six weeks apart. A single session can produce visible improvement, but a course delivers longer-lasting results. We build your plan at your consultation, based on your skin and your goals.
Downtime
Exosome treatment has minimal downtime. When applied after microneedling, you may experience redness for 24 to 48 hours. Applied topically without a prior needling procedure, most clients return to their normal routine the same day.
Timeline for results
You may notice an initial improvement in glow and hydration within the first week. The deeper regenerative effects — firmer skin, reduced fine lines, improved texture — develop over six to twelve weeks as collagen production builds.
Your treatment starts with a free consultation. We assess your skin, talk through your concerns, and confirm whether exosome therapy is the right fit — or whether it would work best as part of a combined plan.
The exosome solution is applied directly to the skin or injected, depending on the area and the outcome we are working towards. For scalp treatments, the solution is delivered into the dermal layer. For facial rejuvenation, we often apply exosomes immediately after a microneedling procedure to maximise absorption and results.
The appointment typically takes 30 to 60 minutes, including preparation and aftercare guidance.
Sessions needed
Most clients start with a course of two to three sessions, spaced four to six weeks apart. A single session can produce visible improvement, but a course delivers longer-lasting results. We build your plan at your consultation, based on your skin and your goals.
Downtime
Exosome treatment has minimal downtime. When applied after microneedling, you may experience redness for 24 to 48 hours. Applied topically without a prior needling procedure, most clients return to their normal routine the same day.
Timeline for results
You may notice an initial improvement in glow and hydration within the first week. The deeper regenerative effects — firmer skin, reduced fine lines, improved texture — develop over six to twelve weeks as collagen production builds.
Who is it for
Exosome treatment works well for a wide range of clients. You are likely a good candidate if you:
- Want to address early to moderate signs of ageing without surgical intervention - Have dull, fatigued or uneven skin tone - Are experiencing fine lines, loss of elasticity or crepey texture - Want to enhance and extend the results of HIFU, RF microneedling or laser treatment - Are concerned about early hair thinning or want to support scalp health - Have sensitive or reactive skin — exosomes are well tolerated and do not rely on injecting foreign substances
We also use exosomes as a post-procedure treatment. Applied after more intensive treatments, they support the skin's healing response and improve the final outcome.
If you are unsure whether exosome treatment is right for you, your free consultation is the right place to find out. We give you an honest assessment and a clear recommendation.
- Want to address early to moderate signs of ageing without surgical intervention - Have dull, fatigued or uneven skin tone - Are experiencing fine lines, loss of elasticity or crepey texture - Want to enhance and extend the results of HIFU, RF microneedling or laser treatment - Are concerned about early hair thinning or want to support scalp health - Have sensitive or reactive skin — exosomes are well tolerated and do not rely on injecting foreign substances
We also use exosomes as a post-procedure treatment. Applied after more intensive treatments, they support the skin's healing response and improve the final outcome.
If you are unsure whether exosome treatment is right for you, your free consultation is the right place to find out. We give you an honest assessment and a clear recommendation.
Exosomes and other treatments
Exosome therapy is particularly effective when used as part of a wider treatment plan. Here is how it combines with other treatments we offer at Changes Clinic:
HIFU (High Intensity Focused Ultrasound): HIFU tightens deeper tissue layers. Exosomes applied after HIFU support skin recovery and amplify the regenerative response in the weeks that follow.
RF microneedling: Applying exosomes immediately after RF microneedling is one of the most effective combinations available. The micro-channels created during needling allow the exosome solution to penetrate more deeply, and the exosomes then support and enhance the collagen remodelling that follows.
Skin boosters and polynucleotides: These treatments address hydration and skin quality from different angles. Combining exosomes with skin boosters or polynucleotides gives the skin a more complete stimulus for renewal.
Chemical peels and laser: For clients working through a peel or laser programme, exosomes can be introduced during the recovery phase to shorten downtime and support better skin quality throughout the course.
Your qualified, experienced & insured practitioner will advise on the most effective sequence and combination for your skin at your consultation.
HIFU (High Intensity Focused Ultrasound): HIFU tightens deeper tissue layers. Exosomes applied after HIFU support skin recovery and amplify the regenerative response in the weeks that follow.
RF microneedling: Applying exosomes immediately after RF microneedling is one of the most effective combinations available. The micro-channels created during needling allow the exosome solution to penetrate more deeply, and the exosomes then support and enhance the collagen remodelling that follows.
Skin boosters and polynucleotides: These treatments address hydration and skin quality from different angles. Combining exosomes with skin boosters or polynucleotides gives the skin a more complete stimulus for renewal.
Chemical peels and laser: For clients working through a peel or laser programme, exosomes can be introduced during the recovery phase to shorten downtime and support better skin quality throughout the course.
Your qualified, experienced & insured practitioner will advise on the most effective sequence and combination for your skin at your consultation.
Testimonials
What our clients say
RAD
2 months ago
Very happy with my consultation. I got the answers I was hoping for and I will soon be booking myself in for a quick and easy mole/sun spot removal.
I now have a new understanding of what the problem is and what has caused it. Thank you.
josephine C.
2 months ago
Even though I couldn't have the treatment I wanted Carly was very helpful and knowledgeable
Kelvin W.
2 months ago
I went for an ultrasound scan due the NHS appointment waiting time was a longtime away, the service I recieved from Andrea was excellent, second to none, Andrea explained everything including the results of the scan straight afterwards.
Jay
3 months ago
I’ve suffered with rosacea for several years and have tried all sorts of creams, skincare routines and products, but nothing really made a lasting difference.
Looking after my skin and being mindful of my diet definitely helps to keep it under control, but IPL at Changes Clinic has made the biggest difference by far. The redness in my face has reduced so much, and even when I do get a flare up, it’s nowhere near as bad as it used to be because the underlying redness has improved so much.
Everyone at Changes Clinic has been friendly, professional and really knowledgeable. They’ve always taken the time to answer any questions and made me feel comfortable throughout the whole process.
I’d happily recommend Changes Clinic to anyone who suffers from rosacea and is thinking about IPL. It’s made a huge difference to my skin and has given me so much more confidence.
Lee B.
3 months ago
It’s the first time I’ve done something like this. What a lovely place & people. Very kind, polite & efficient. Very impressed with my procedure, obviously, it hasn’t healed yet, but will definitely be back for more treatment & also considering other treatments too. Well impressed and everything was explained as the treatment was carried out, pleasantly surprised, thank you so much for taking such good care of my skin. Lee B
duncan T.
5 months ago
Changes Clinic provides a super professional and very competitively priced service, I’ve just completed two sessions to have some skin lesions removed and I was very well looked after ands made to feel at ease with the whole process. I would recommend them for anybody needing similar services.
Maria K.
5 months ago
Absolutely exceptional service and results. This clinic combines professionalism, expertise, and luxury perfectly. The team are incredibly skilled and attentive, and every visit feels calm, personalised, and premium.
Alex G.
5 months ago
I had PRP Hair Treatment, with Sumayiah, she is very friendly, she takes the time to explain the procedure and really makes sure to focus on target areas.
I have had 2 treatments so far and I already see a difference in my hair density and texture. She can use a gun or syringe, the syringe goes deeper and achieves better results, so its worth asking for the syringe method.
I combined my PRP with Calecim serum and that gives an even greater boost. So I recomend you sign up and ask for a booking with Sumaiyah, you'll be very happy that you did..
Alex G.
5 months ago
I had PRP Hair Treatment, with Sumayiah, she is very friendly, she takes the time to explain the procedure and really makes sure to focus on target areas.I have had 2 treatments so far and I already see a difference in my hair density and texture. She can use a gun or syringe, the syringe goes deeper and achieves better results, so its worth asking for the syringe method.I combined my PRP with Calecim serum and that gives an even greater boost. So I recomend you sign up and ask for a booking with Sumaiyah, you'll be very happy that you did..
Darcy S.
5 months ago
Been to changes this morning, staff was very welcoming and I had the perfect treatments. Will be returning!♥️
Laurie loz L
6 months ago
Very good, the massage lady knows what's she is doing. Definitely worth a visit or 3
Emile J.
7 months ago
One of the best decisions I’ve made for my skin! The treatments are effective, safe, and handled by experienced professionals. I struggled with acne for years, and after visiting this clinic, I finally see clear and healthy skin.
The staff always follows up after treatments, which shows how much they care about their clients’ progress. Their attention to detail and dedication to customer satisfaction is truly impressive. I would highly recommend this clinic to anyone who wants real results and excellent service.
Aitch O.
7 months ago
Lovely relaxed atmosphere with great staff. My lazer hair removal was undertaken by two very capable proffessional young women Kelly and Surmaiyah. Both demonstrate constant care and ensure this not always comfortable experience is as pleasant as possible. The facility is immaculately clean and there is excellent visitor free parking available.
I have no hesitation in recommending the clinic to others and whilst I can only comment on the treatments I have received to date I will be availing myself of some of the others services offered.
Pamela K.
8 months ago
I am so glad I visited the Changes Clinic today for an upper abdominal ultrasound. I was a nervous wreck as I have a bit of a phobia of scans & Andrea was just brilliant with me. So reassuring, she went above & beyond with careful detailed descriptions, even went over some areas twice just for extra reassurance. I left smiling with a huge weight lifted off my shoulders. I have already recommended to a friend & highly recommend to anyone experiencing symptoms they’d like some extra peace of mind for. Was also really easy to book & communication excellent throughout. Thank you so much!!
Mayumi F.
8 months ago
I’ve been attending changes for facial hair removal for about 6 months now and I can honestly say it’s been one of the best and easiest experiences for me. Sumaiyah has been amazing through every step. From consultation to our current progress. She shows great professionalism, compassion, consideration -especially when I’m having a bad pain tolerance day- and is very meticulous in which the results are to show for it. Every appointment I get a little nervous and Sumaiyah has always put my nerves at ease and worked at a pace that suits me and my needs. I’m very thankful to work with her and be attending changes clinic. I would recommend their treatment. The staff are very welcoming. Adriana Verrier :) .
Mayumi F.
8 months ago
I’ve been attending changes for facial hair removal for about 6 months now and I can honestly say it’s been one of the best and easiest experiences for me. Sumaiyah has been amazing through every step. From consultation to our current progress. She shows great professionalism, compassion, consideration -especially when I’m having a bad pain tolerance day- and is very meticulous in which the results are to show for it. Every appointment I get a little nervous and Sumaiyah has always put my nerves at ease and worked at a pace that suits me and my needs. I’m very thankful to work with her and be attending changes clinic. I would recommend their treatment. The staff are very welcoming. Adriana Verrier 🙂 .
Monnia L.
9 months ago
Andrea provides a highly professional and exceptional service. With over 20 years NHS experience you are in good hands. Any issues and their significance are explained in full. A highly recommended health screening and well-being service.
Charlie Jane Y.
10 months ago
I had an amazing experience — very friendly and welcoming from the moment I arrived. She was super helpful, incredibly knowledgeable, and truly professional throughout. She made me feel completely at ease. Such a down-to-earth lady that you can feel genuinely comfortable with. Her prices are so reasonable and very affordable too. I highly recommend Andrea
Garry H.
2 years ago
Chloe was very well informed and helpful. There was probably too much information to absorb in the time span, and more published literature would be helpful (FAQs, prices, offers, medical considerations etc)
Linda D.
2 years ago
Such wonderful staff. Professional, yet friendly to keep any worries at bay. Thank you all for being so amazing and supportive!! Linda & Pippa Docherty
stephen G.
2 years ago
Great work on my lipoma. Can’t remember the ladies name. Naomi or Natasha? Was lovely. How is she a grandmother???
Karen F
2 years ago
A warm and friendly welcome at this beautiful clinic. Practitioners were excellent, explaining the treatment and after care and putting me at complete ease. I’m looking forward to seeing the results of my first Focus Dual Radio Frequency Needling treatment. Thank you Changes!
Taya
2 years ago
Lovely experience! The staff were friendly and helpful. They listened to me about what I wanted and answered all my questions. Naomi was very professional and I was very happy with my consultation. I look forward to returning for my treatment.
Common questions
How is exosome treatment different from PRP?
PRP (platelet-rich plasma) therapy uses growth factors concentrated from your own blood, which are then injected or applied to the treatment area. Its effectiveness depends in part on the quality and concentration of your own platelets. Exosome therapy works differently. It operates through cellular signalling rather than growth factor delivery, and it is not dependent on your own blood. Exosome solutions contain a standardised, high concentration of signalling molecules, which makes the treatment more consistent and predictable across different clients. Many practitioners now regard exosomes as a more advanced option than PRP.
How many sessions will I need?
Most clients benefit from a course of two to three sessions, spaced four to six weeks apart. The exact number depends on your skin and what you want to achieve. We agree on your plan at your consultation and review your results as treatment progresses.
Is there any downtime?
Exosome treatment itself has minimal downtime. As a standalone treatment, most clients return to their normal routine the same day. When exosomes are combined with RF microneedling or another needling procedure, you may experience redness and mild sensitivity for 24 to 48 hours. We give you specific aftercare guidance at your appointment.
Who performs exosome treatment at Changes Clinic?
All exosome treatments are carried out by our qualified, experienced & insured practitioners. Changes Clinic is CQC-registered, and our practitioners hold VTCT Level 3 to Level 5 qualifications. Your free consultation is with a qualified, experienced & insured practitioner who will assess your skin and recommend the right approach.
Gallery
Book your free consultation
Talk to a qualified, experienced & insured practitioner, ask your questions, and decide if it is right for you. No obligation to book on the day.
Contact
Get in touch
Phone
02392 382000
WhatsApp
07710 096718
Address
1000 Lakeside, North Harbour, Western Road, Portsmouth, PO6 3EN
Lumi Eyes
Lumi Eyes is a polynucleotide eye treatment for dark circles, hollowness and fine lines. Book your free consultation at Changes Clinic Portsmouth today.
Profhilo
Profhilo in Portsmouth. Injectable bio-remodelling that hydrates, firms and smooths skin naturally. Free consultation at Changes Clinic. Book today.
Chemical Peel
Chemical peels in Portsmouth for acne, pigmentation, fine lines and uneven tone. Tailored for every skin type. Free consultation at Changes Clinic.
Hydrafacial
Hydrafacial in Portsmouth. Deep cleanse, exfoliate and hydrate in one treatment. Instant results, no downtime. Free consultation at Changes Clinic.
Dermaplaning
Dermaplaning in Portsmouth. Removes dead skin and peach fuzz for smoother, brighter skin. No downtime. Book your free consultation at Changes Clinic.
Microneedling
Microneedling in Portsmouth to boost collagen, reduce scarring and smooth skin texture. Minimal downtime. Free consultation at Changes Clinic. Book today.
Obagi Skincare
Obagi medical-grade skincare at Changes Clinic Portsmouth. Expert advice on the right system for your skin. Book a free skincare consultation today.
Calecim
Calecim in Portsmouth. Growth factors and exosomes to repair, firm and refresh skin. Paired with microneedling for deeper results. Book today.
Skintrinsiq
Skintrinsiq facial in Portsmouth. Clears pores, infuses Obagi actives and leaves skin visibly fresher in under an hour. Free consultation. Book today.
IPL Skin Therapy
IPL skin therapy in Portsmouth for pigmentation, sun damage, rosacea and redness. Clearer skin with minimal downtime. Book at Changes Clinic today.
PRP Skin Treatment
PRP skin treatment in Portsmouth stimulates collagen, improves skin texture and reduces fine lines using your own plasma. Free consultation. Book today.
The Emerald Healer
Holistic treatments in Portsmouth with Laura McBride, The Emerald Healer. Reiki, massage, lymphatic drainage and more. Book at Changes Clinic today.