Mesotherapy Portsmouth

Mesotherapy is not a topical product. It does not sit on the surface of your skin and wait for absorption. It places active ingredients exactly where the skin needs them — delivered just below the surface using very fine needles, bypassing the skin barrier entirely.

The cocktail includes vitamins, minerals, amino acids and hyaluronic acid. Your skin receives them directly in the dermis, where new cells form and collagen fibres are maintained. The result is skin that looks brighter, more hydrated and more even in tone and texture — because it has been nourished at the source. We also have exosome and stem cell products post treatment & to take away.

Our qualified, experienced & insured practitioners tailor every mesotherapy treatment to your skin at Changes Clinic in Cosham, Portsmouth. Your first consultation is free.

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Treatment time 30 to 45 minutes
Sessions Course of 3 to 6 recommended
Maintenance Every 1 to 3 months
From £200

What mesotherapy treats

Mesotherapy addresses a wide range of skin concerns by delivering active ingredients directly into the layer of tissue where they have the most effect.

Dull and dehydrated skin

Hyaluronic acid delivered into the dermis provides deep hydration that topical creams cannot replicate. Many clients describe their skin as looking lit from within after a course of treatment.

Fine lines and early ageing

The vitamin and amino acid blend supports collagen production and cell renewal. Fine surface lines caused by dehydration and early ageing visibly improve across a course of sessions.

Uneven tone and pigmentation

Antioxidants and brightening agents in the cocktail work on post-inflammatory pigmentation, uneven tone and general dullness over time, improving skin clarity and consistency.

Areas we treat

We use mesotherapy on the face, neck, decolletage, hands and scalp. Scalp mesotherapy supports circulation and delivers nutrients directly to the follicle area, making it a useful treatment alongside PRP for hair.

How it works

A mesotherapy treatment uses a series of very fine micro-injections to place the active cocktail just below the skin surface. The needles penetrate only one to four millimetres, reaching the mesoderm layer where skin cells are produced and where collagen and elastin are maintained.

The cocktail we use contains hyaluronic acid for hydration, vitamins and antioxidants to support cell function, amino acids for skin structure, and minerals that support the skin's natural repair processes. The exact blend is adjusted to your skin concerns at consultation.

Because the ingredients bypass the skin barrier entirely, the amounts delivered to the target tissue are far greater than anything a topical product can achieve. The skin responds directly, which is why results are visible quickly.

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What to expect

Most clients notice an improvement in hydration and glow after a single session. The skin looks fresher and more alive within a day or two, once any minor redness at the injection sites settles.

Deeper improvements in tone, texture and line reduction build across a course. We recommend three to six sessions, spaced two to three weeks apart. After the course, maintenance sessions every one to three months keep the skin in good condition between more intensive treatments.

Downtime is minimal. Mild redness at the injection sites is normal and typically settles within a few hours. Most clients return to their normal routine on the same day.

Practitioner assessing a client's face during a consultation

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Videos

Treatment in action

What mesotherapy involves

Our practitioner talks through the treatment before it starts.

Mesotherapy to the face

A course of micro-injections delivered across the treatment area.

Mesotherapy to the neck

The same technique applied to the neck and décolletage.

Testimonials

What our clients say

RAD

2 months ago

Very happy with my consultation. I got the answers I was hoping for and I will soon be booking myself in for a quick and easy mole/sun spot removal. I now have a new understanding of what the problem is and what has caused it. Thank you.

josephine C.

2 months ago

Even though I couldn't have the treatment I wanted Carly was very helpful and knowledgeable

Kelvin W.

2 months ago

I went for an ultrasound scan due the NHS appointment waiting time was a longtime away, the service I recieved from Andrea was excellent, second to none, Andrea explained everything including the results of the scan straight afterwards.

Jay

3 months ago

I’ve suffered with rosacea for several years and have tried all sorts of creams, skincare routines and products, but nothing really made a lasting difference. Looking after my skin and being mindful of my diet definitely helps to keep it under control, but IPL at Changes Clinic has made the biggest difference by far. The redness in my face has reduced so much, and even when I do get a flare up, it’s nowhere near as bad as it used to be because the underlying redness has improved so much. Everyone at Changes Clinic has been friendly, professional and really knowledgeable. They’ve always taken the time to answer any questions and made me feel comfortable throughout the whole process. I’d happily recommend Changes Clinic to anyone who suffers from rosacea and is thinking about IPL. It’s made a huge difference to my skin and has given me so much more confidence.

Lee B.

3 months ago

It’s the first time I’ve done something like this. What a lovely place & people. Very kind, polite & efficient. Very impressed with my procedure, obviously, it hasn’t healed yet, but will definitely be back for more treatment & also considering other treatments too. Well impressed and everything was explained as the treatment was carried out, pleasantly surprised, thank you so much for taking such good care of my skin. Lee B

duncan T.

5 months ago

Changes Clinic provides a super professional and very competitively priced service, I’ve just completed two sessions to have some skin lesions removed and I was very well looked after ands made to feel at ease with the whole process. I would recommend them for anybody needing similar services.

Maria K.

5 months ago

Absolutely exceptional service and results. This clinic combines professionalism, expertise, and luxury perfectly. The team are incredibly skilled and attentive, and every visit feels calm, personalised, and premium.

Alex G.

5 months ago

I had PRP Hair Treatment, with Sumayiah, she is very friendly, she takes the time to explain the procedure and really makes sure to focus on target areas. I have had 2 treatments so far and I already see a difference in my hair density and texture. She can use a gun or syringe, the syringe goes deeper and achieves better results, so its worth asking for the syringe method. I combined my PRP with Calecim serum and that gives an even greater boost. So I recomend you sign up and ask for a booking with Sumaiyah, you'll be very happy that you did..

Alex G.

5 months ago

I had PRP Hair Treatment, with Sumayiah, she is very friendly, she takes the time to explain the procedure and really makes sure to focus on target areas.I have had 2 treatments so far and I already see a difference in my hair density and texture. She can use a gun or syringe, the syringe goes deeper and achieves better results, so its worth asking for the syringe method.I combined my PRP with Calecim serum and that gives an even greater boost. So I recomend you sign up and ask for a booking with Sumaiyah, you'll be very happy that you did..

Darcy S.

5 months ago

Been to changes this morning, staff was very welcoming and I had the perfect treatments. Will be returning!♥️

Laurie loz L

6 months ago

Very good, the massage lady knows what's she is doing. Definitely worth a visit or 3

Emile J.

7 months ago

One of the best decisions I’ve made for my skin! The treatments are effective, safe, and handled by experienced professionals. I struggled with acne for years, and after visiting this clinic, I finally see clear and healthy skin. The staff always follows up after treatments, which shows how much they care about their clients’ progress. Their attention to detail and dedication to customer satisfaction is truly impressive. I would highly recommend this clinic to anyone who wants real results and excellent service.

Aitch O.

7 months ago

Lovely relaxed atmosphere with great staff. My lazer hair removal was undertaken by two very capable proffessional young women Kelly and Surmaiyah. Both demonstrate constant care and ensure this not always comfortable experience is as pleasant as possible. The facility is immaculately clean and there is excellent visitor free parking available. I have no hesitation in recommending the clinic to others and whilst I can only comment on the treatments I have received to date I will be availing myself of some of the others services offered.

Pamela K.

8 months ago

I am so glad I visited the Changes Clinic today for an upper abdominal ultrasound. I was a nervous wreck as I have a bit of a phobia of scans & Andrea was just brilliant with me. So reassuring, she went above & beyond with careful detailed descriptions, even went over some areas twice just for extra reassurance. I left smiling with a huge weight lifted off my shoulders. I have already recommended to a friend & highly recommend to anyone experiencing symptoms they’d like some extra peace of mind for. Was also really easy to book & communication excellent throughout. Thank you so much!!

Mayumi F.

8 months ago

I’ve been attending changes for facial hair removal for about 6 months now and I can honestly say it’s been one of the best and easiest experiences for me. Sumaiyah has been amazing through every step. From consultation to our current progress. She shows great professionalism, compassion, consideration -especially when I’m having a bad pain tolerance day- and is very meticulous in which the results are to show for it. Every appointment I get a little nervous and Sumaiyah has always put my nerves at ease and worked at a pace that suits me and my needs. I’m very thankful to work with her and be attending changes clinic. I would recommend their treatment. The staff are very welcoming. Adriana Verrier :) .

Mayumi F.

8 months ago

Monnia L.

9 months ago

Andrea provides a highly professional and exceptional service. With over 20 years NHS experience you are in good hands. Any issues and their significance are explained in full. A highly recommended health screening and well-being service.

Charlie Jane Y.

10 months ago

I had an amazing experience — very friendly and welcoming from the moment I arrived. She was super helpful, incredibly knowledgeable, and truly professional throughout. She made me feel completely at ease. Such a down-to-earth lady that you can feel genuinely comfortable with. Her prices are so reasonable and very affordable too. I highly recommend Andrea

Garry H.

2 years ago

Chloe was very well informed and helpful. There was probably too much information to absorb in the time span, and more published literature would be helpful (FAQs, prices, offers, medical considerations etc)

Linda D.

2 years ago

Such wonderful staff. Professional, yet friendly to keep any worries at bay. Thank you all for being so amazing and supportive!! Linda & Pippa Docherty

stephen G.

2 years ago

Great work on my lipoma. Can’t remember the ladies name. Naomi or Natasha? Was lovely. How is she a grandmother???

Karen F

2 years ago

A warm and friendly welcome at this beautiful clinic. Practitioners were excellent, explaining the treatment and after care and putting me at complete ease. I’m looking forward to seeing the results of my first Focus Dual Radio Frequency Needling treatment. Thank you Changes!

Taya

2 years ago

Lovely experience! The staff were friendly and helpful. They listened to me about what I wanted and answered all my questions. Naomi was very professional and I was very happy with my consultation. I look forward to returning for my treatment.

Common questions

How many sessions do I need?

We recommend a course of three to six sessions, spaced two to three weeks apart. Most clients see a clear improvement across the course. Ongoing maintenance sessions every one to three months can keep the results consistent.

Is mesotherapy painful?

The needles are very fine and most clients find the treatment comfortable throughout. If you prefer, we apply a numbing cream before we start.

Who is mesotherapy suitable for?

Mesotherapy suits most skin types and tones. We assess your skin at the free consultation and tailor the cocktail blend to your specific concerns. If a different treatment would serve you better, we will tell you at that stage.

Can it be combined with other treatments?

Yes. Mesotherapy pairs well with microneedling and chemical peels as part of a wider skin plan. We will recommend the right combination for your skin at your free consultation.